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Rev. peru. med. exp. salud publica ; 36(4): 681-686, oct.-dic. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1058779

ABSTRACT

RESUMEN Con el objetivo de determinar el efecto del consumo de harina de cáscara o harina de pulpa de dos variedades de Solanum tuberosum (papa Yungay y papa Canchán) sobre la acumulación de tejido adiposo, peso de órganos y estrés oxidativo en hígado de ratas realizamos un estudio experimental en 24 ratas Holtzman obesas, divididos en cuatro grupos y, sometidas a dietas que contenían 10% de harina de las dos variedades de papa. Los grupos fueron T1: cáscara Yungay, T2: pulpa Yungay; T3: cáscara Canchán; y T4: pulpa Canchán. Al finalizar, se sacrificaron todos los animales para registrar los pesos de órganos y tejido adiposo, y extraer muestras para determinar la actividad enzimática de superóxido dismutasa y catalasa en el hígado. El grupo de ratas obesas que consumió pulpa de variedad Yungay tuvo menor estrés oxidativo en el hígado; además, independientemente de la parte de tubérculo consumido, esta variedad redujo el peso de los riñones.


ABSTRACT This study aimed to determine the effect of the consumption of peel flour or pulp flour from two varieties of Solanum tuberosum (Yungay potato and Canchán potato) on the accumulation of adipose tissue, organ weight, and oxidative stress in the liver of rats. We carried out an experimental study in 24 obese Holtzman rats, divided into four groups and subjected to diets containing 10% flour from both varieties of potato. The groups were T1: Yungay peel; T2: Yungay pulp; T3: Canchán peel; and T4: Canchán pulp. When the study was completed, all the animals were slaughtered to record the weights of organs and adipose tissue and to extract samples to determine the enzyme activity of superoxide dismutase and catalase in the liver. The group of obese rats that consumed the pulp of the Yungay variety had less oxidative stress in the liver. Also, regardless of the tuber part consumed, this variety reduced the weight of the kidneys.


Subject(s)
Animals , Male , Rats , Solanum tuberosum/chemistry , Plant Extracts/pharmacology , Oxidative Stress/drug effects , Obesity/drug therapy , Organ Size/drug effects , Adipose Tissue/drug effects , Rats, Sprague-Dawley , Kidney/drug effects , Kidney/metabolism , Liver/drug effects , Liver/metabolism
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